The Texans and Buccaneers were in position, but they ultimately failed to do the San Francisco 49ers any favors Sunday.
Both teams lost in disappointing fashion on their home fields to the Seahawks and Cardinals, respectively. At 2-2 through the first quarter of the season, San Francisco still finds itself trailing Seattle by two games and tied with Arizona in the NFC West after its win over the last-place Rams Thursday night.
The Texans, who put up more yardage against the Seahawks in the first half than any team had in an entire game this year, blew a 17-point lead before losing in overtime, 23-20.
"They handed it to us every way they wanted to in the first half and we didn't have any answer to stop it," Pete Carroll told reporters following the game. "The challenge that we all wanted to meet up to was we hadn't showed who we were and how we could play."
The Seahawks' comeback was highlighted by Richard Sherman's 58-yard interception return for a touchdown to tie it with 2:51 left in regulation. It was the third interception returned for a score thrown by Matt Schaub in as many weeks, as Houston fell to 2-2.
Had the Texans maintained their lead against the Seahawks, the defending NFC champions would be just one game back in the standings despite a disappointing start to the season. San Francisco will host Houston Sunday night and has a favorable schedule leading up to its bye in Week 9.
After next week, the 49ers will host the Cardinals, then travel to 3-1 Tennessee - who lost quarterback Jake Locker to a hip injury Sunday - and London to play the win-less Jaguars.
Tampa Bay came out of Sunday still looking for its first victory after allowing 13 points in the fourth quarter to lose by just 3. Behind rookie quarterback Mike Glennon, the Buccs shut out Carson Palmer's offense for the first 56:48 before hitting Larry Fitzgerald for a 13-yard score following Glennon's first of two interceptions in the last 3:23.
Tampa's offense then went three-and-out, leading to Arizona's 29-yard drive resulting in the go-ahead, 27-yard field goal from Jay Feely. When the Buccaneers got the ball back, Glennon threw his second interception to Patrick Peterson, thwarting their chance at a comeback.
Glennon's performance comes after a week of turmoil in Tampa Bay as coach Greg Schiano benched former first-round pick Josh Freeman after failing to complete 50 percent of his throws in the season's first three games. The Buccaneers had lost eight of his last nine starts dating back to 2012. Freeman wasn't active Sunday.
"With all the happenings of the week, it was the best thing for our team," Schiano said. "There's stuff that I'm not going to get into, but that was the best thing for our football team."
The Seahawks (4-0) will play their second-straight road game next week when they take on Indianapolis (3-1) before getting the Titans (3-1) at home. Before coming to San Francisco in two weeks, the Cardinals host the Carolina Panthers (1-2), who are coming off a bye.
The Associated Press contributed to this report.
Follow Editor in Chief Chris Biderman on Twitter.